HCID 22278866, 화합물 → 3-Ethylpiperidin-4-amine

HRID 1063291노트

반응식

HRID 1063291 반응식
[NH2:1][CH:2]1[CH2:7][CH2:6][N:5](C(OCC)=O)[CH2:4][CH:3]1[CH2:13][CH3:14]>[OH-].[Na+]>[NH2:1][CH:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH:3]1[CH2:13][CH3:14]

참가 물질

3

반응물 1

HCID 22278866HCID 22278866, 화합물

생성물 1

HCID 219737733-Ethylpiperidin-4-amine

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매

반응 조건

온도
120 °C

실험 절차

4-Amino-1-carbethoxy-3-ethylpiperidine was suspended in 5 M NaOH solution (36 ml), stirred at 120° C. for 120 hr, cooled, extracted with ethyl acetate, dried (Na2SO4) and concentrated to dryness to afford 4-amino-3-ethylpiperidine. Yield 3.1 g (59.6%), C7H16N2, m/z 129 (M+1).

후처리

  1. temperaturecooled
  2. extractionextracted with ethyl acetate
  3. dry with materialdried (Na2SO4)
  4. concentrationconcentrated to dryness

출처 및 근거

ORD 기록
ord-c1cb56e5354f42409e54cc59addb8577
출처 데이터셋
uspto-grants-2005_11
특허 번호
US06964966B2

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