Hydrochloric Acid → HCID 9928554, 화합물

HRID 1064076노트

반응식

HRID 1064076 반응식
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([N:14]2[C:18]([C:19]3[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=3)=[C:17]([C:25]3[CH:30]=[CH:29][C:28]([Cl:31])=[CH:27][CH:26]=3)[C:16](=[O:32])[NH:15]2)[CH2:10][CH2:9]1)=O)(C)(C)C.Cl>CCOCC.O1CCOCC1>[Cl:31][C:28]1[CH:29]=[CH:30][C:25]([C:17]2[C:16](=[O:32])[NH:15][N:14]([CH:11]3[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]3)[C:18]=2[C:19]2[CH:20]=[CH:21][N:22]=[CH:23][CH:24]=2)=[CH:26][CH:27]=1

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 69357048HCID 69357048, 화합물

생성물 1

HCID 9928554HCID 9928554, 화합물

시약·촉매·용매 2

HCID 3283Diethyl Ether용매HCID 312751,4-Dioxane용매

실험 절차

To a solution of 4-[4-(4-Chloro-phenyl)-3-oxo-5-pyridin-4-yl-2,3-dihydro-pyrazol-1-yl]-piperidine-1-carboxylic acid tert-butyl ester 200 mg in flask was added HCl in ether and dioxane. After 2.25 hours, the solvent was evaporated under reduced pressure to afford the title compound as yellow oil. MS (ES+): 355 (M+H)+; (ES−): 353 (M−H).

후처리

  1. customthe solvent was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-f3227960537d4a8588a4dfe254704bf8
출처 데이터셋
uspto-grants-2005_11
특허 번호
US06967254B2

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