2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → 6-(4-Phenylsulfonyl-butoxy)-carbostyril
반응식
[C:1]1([S:7]([CH2:10][CH2:11][CH2:12][CH2:13][O:14][C:15]2[CH:16]=[C:17]3[C:22](=[CH:23][CH:24]=2)[NH:21][C:20](=[O:25])[CH2:19][CH2:18]3)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.ClC1C(=O)C(C#N)=C(C#N)C(=O)C=1Cl>>[C:1]1([S:7]([CH2:10][CH2:11][CH2:12][CH2:13][O:14][C:15]2[CH:16]=[C:17]3[C:22](=[CH:23][CH:24]=2)[NH:21][C:20](=[O:25])[CH:19]=[CH:18]3)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1참가 물질
3
실험 절차
Prepared analogous to Example 86 from 6-(4-phenylsulfonyl-butoxy)-3,4-dihydro-carbostyril and 2,3-dichloro-5,6-dicyano-benzoquinone. Purification was carried out by column chromatography on silica gel (particle size: 0.2-0.5 mm) with chloroform/methanol/ethyl acetate=4/1/1.
후처리
- customPurification
출처 및 근거
- ORD 기록
- ord-27ca20ae64794dc7a313d888219e2851
- 출처 데이터셋
- uspto-grants-1982_05