Sodium Carbonate → 2-Bromo-4-thiocyanatoaniline
반응식
[Br:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].[S-:9][C:10]#[N:11].[Na+].BrBr.[Br-].[Na+].C(=O)([O-])[O-].[Na+].[Na+]>CO.O>[Br:1][C:2]1[CH:8]=[C:7]([S:9][C:10]#[N:11])[CH:6]=[CH:5][C:3]=1[NH2:4]참가 물질
8
실험 절차
To a cold (0°-5° C.), stirred solution of o-bromoaniline (20.6 g., 0.12 mole) and sodium thiocyanate (29.2 g., 0.36 mole) in methanol (300 ml.) is added dropwise a solution of bromine (19.5 g., 0.122 mole) in methanol (75 ml.) saturated with sodium bromide. The solution is stirred for one hour following the addition of the bromine and then poured into water (2 liters) and neutralized with sodium carbonate. The resulting solid is collected, washed with water and dried, m.p. 74°-79° C., yield 96% of theoretical.
후처리
- customThe resulting solid is collected
- washwashed with water
- customdried
출처 및 근거
- ORD 기록
- ord-c3b15695cbfd4b5c92e40906f7a10a57
- 출처 데이터셋
- uspto-grants-1982_05
- 특허 번호
- US04331817
반응 노트
불러오는 중…
