Acetic Anhydride → (1-Acetylpiperidin-4-yl)acetic acid

HRID 1066311노트

반응식

HRID 1066311 반응식
[NH:1]1[CH2:6][CH2:5][CH:4]([CH2:7][C:8]([OH:10])=[O:9])[CH2:3][CH2:2]1.[C:11](OC(=O)C)(=[O:13])[CH3:12]>>[C:11]([N:1]1[CH2:6][CH2:5][CH:4]([CH2:7][C:8]([OH:10])=[O:9])[CH2:3][CH2:2]1)(=[O:13])[CH3:12]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 15125944-Piperidineacetic acid

생성물 1

HCID 10442408(1-Acetylpiperidin-4-yl)acetic acid수율 99%

실험 절차

4-Piperidinylacetic acid (5 grams) (35.0 mmoles) was reacted with acetic anhydride (10.7 grams) (105.0 mmoles) as described in Preparative Example 13A to give the title compound (Yield: 6.4 grams, 99%, MH+ 185).

출처 및 근거

ORD 기록
ord-ecff1cd7cec64851b616981603e56170
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06242458B1

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