Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sorbitan mono-(9Z)-9-octadecenoate → glycerol ascorbic acid Span 80
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sorbitan mono-(9Z)-9-octadecenoate | HCID 9920342 | — |
| 반응물 | L-Ascorbic Acid | HCID 54670067 | — |
| 반응물 | Ascorbic acid glycerol | HCID 131722625 | — |
| 용매 | Glycerol | HCID 753 | — |
| 생성물 | glycerol ascorbic acid Span 80 | HCID 131722624 | — |
반응 단계
L-Ascorbic acid (50 mg) was dissolved in a 1 mL glycerol solution by heating and stirring the mixture. After being cooled to room temperature, the ascorbic acid/glycerol solution was mixed with GCSF powder (45.3 mg) and Span 80 (250 mL). 3.75 mL thickened oil (3% AIMS) prepared as described above was added to the G-CSF/ascorbic acid/glycerol mixture and ground together to give a viscous oil suspension (G-CSF/20% glycerol+ascorbic acid/Span 80/3% AIMS/oil).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06245740B1 |
| 출처 데이터셋 | uspto-grants-2001_06 |
| ORD ID | ord-ac8f2f07d82e4924bd96664d332a8bca |
| 출처 메모 | uspto-grants-2001_06 |