Tert-Butyl nitrite → HCID 23445659, 화합물

HRID 1067358

반응식

HRID 1067358 반응식
[Br:1][C:2]1[CH:8]=[C:7]([CH2:9][CH3:10])[C:5]([NH2:6])=[C:4]([CH2:11][CH3:12])[CH:3]=1.[F:13][B-:14]([F:17])([F:16])[F:15].[H+].[N:19](OC(C)(C)C)=O>C(O)C>[F:13][B-:14]([F:17])([F:16])[F:15].[Br:1][C:2]1[CH:8]=[C:7]([CH2:9][CH3:10])[C:5]([N+:6]#[N:19])=[C:4]([CH2:11][CH3:12])[CH:3]=1

참가 물질

5

반응물 3

HCID 10906Tert-Butyl nitriteHCID 28118Tetrafluoroboric acidHCID 6114524-Bromo-2,6-diethylaniline

생성물 1

HCID 23445659HCID 23445659, 화합물수율 66%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

At 0° C., to a stirred solution of commercial 4-bromo-2,6-diethylaniline (10.0 g, 43.9 mmol) in absolute ethanol (219 mL) was added 48% aq. tetrafluoroboric acid (17.2 mL), followed by tert-butyl nitrite (5.7 mL, 48.0 mmol). After 0.5 h, the reaction was poured into ice cold ether (877 mL). The resulting precipitate was washed with cold ether and dried to give 9.39 g (66%) of the title compound. 1H NMR: consistent.

후처리

  1. washThe resulting precipitate was washed with cold ether
  2. customdried

출처 및 근거

ORD 기록
ord-b8e222e004b5461f856955c16ca5661e
출처 데이터셋
uspto-grants-2001_06
특허 번호
US06248764B1

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