Hydrochloric Acid → HCID 70108790, 화합물
반응식
[CH2:1]([C:8]1[S:12][C:11]([CH:13]2[CH2:18][CH2:17][N:16](C(OC(C)(C)C)=O)[CH2:15][CH2:14]2)=[N:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:26]>CO>[ClH:26].[CH2:1]([C:8]1[S:12][C:11]([CH:13]2[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]2)=[N:10][CH:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
4
실험 절차
To 37 mg of 4-(5-benzyl-thiazol-2-yl)-1-t-butyloxycarbonyl-piperidine (from Step B) was added 4 ml of a saturated solution of hydrochloric acid in methanol. The reaction was stirred for 3.5 hours at room temperature. The methanol was evaporated under reduced pressure to give 24 mg of the title compound. ESI-MS 259 (M+H); HPLC A: 2.00 min.
후처리
- customThe methanol was evaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-d9e587331de241beb15087ad97b57cbb
- 출처 데이터셋
- uspto-grants-2001_06
- 특허 번호
- US06248755B1
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