참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Nitric Acid | HCID 944 | — |
| 반응물 | 4-Ethylbenzoic Acid | HCID 12086 | — |
| 생성물 | 4-Ethyl-3-nitrobenzoic acid | HCID 8167086 | 94.8% |
반응 단계
4-Ethylbenzoic acid (20 g, 133 mmol) was ice-cooled and fuming nitric acid (94%, d=1.50, 50 ml) was dropwise added thereto for 40 min. The mixture was stirred at 4-5° C. for 1.25 hr. The resulting yellow suspension was poured into ice-water and the precipitated crystals were collected by filtration. The crystals were dissolved in ethanol, and water was added for recrystallization to give the objective compound (24.6 g, 94.8%) as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06911469B2 |
|---|
| 출처 데이터셋 | uspto-grants-2005_06 |
|---|
| ORD ID | ord-1331128ebe094f018cb9c9a4c9071bc9 |
|---|
| 출처 메모 | uspto-grants-2005_06 |
|---|
