Methyl Isocyanate → (R,S)-Bis-(1-methyl-2,5-dioxo-4-imidazolidinyl-methyl)-disulphide

참여 물질

반응 단계

To a mixture of L-cystine (12 g) and 2 molar sodium hydroxide solution (50 ml), cooled to 0°-5° C. in an ice bath, was added, dropwise, methyl isocyanate (8.55 g). The clear solution was stirred at 0° for 2 hours, and then at room temperature over night.

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