Phosphoric Acid → 4-Hydroxy-4-methyl-5-(prop-2-en-1-yl)cyclopent-2-en-1-one

HRID 1073695노트

반응식

HRID 1073695 반응식
[CH3:1][C:2]1[O:11][C:5]([CH:6](O)[CH2:7][CH:8]=[CH2:9])=[CH:4][CH:3]=1.P([O-])([O-])(O)=[O:13].[K+].[K+].P(=O)(O)(O)O>O>[CH2:7]([CH:6]1[C:2]([OH:11])([CH3:1])[CH:3]=[CH:4][C:5]1=[O:13])[CH:8]=[CH2:9]

참가 물질

5

반응물 3

HCID 1004Phosphoric AcidHCID 24450Potassium Phosphate, DibasicHCID 110625572-(1-hydroxy-3-butenyl)-5-methyl furan

생성물 1

HCID 128798724-Hydroxy-4-methyl-5-(prop-2-en-1-yl)cyclopent-2-en-1-one수율 80%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

In the same apparatus as in Example 1, 5-methyl-allyl-furfuryl alcohol (50 parts) and a buffer solution prepared from water (1500 parts) and dipotassium monohydrogen phosphate (1.7 parts) and adjusted to pH 5.1 with phosphoric acid were charged, and the resultant mixture was stirred at 100° C. in a nitrogen stream until the starting compound was consumed. The reaction mixture was treated as in Example 1 to give 2-allyl-3-hydroxy-3-methyl-4-cyclopentenone in a yield of 80 %.

후처리

  1. additionwere charged
  2. customwas consumed
  3. additionThe reaction mixture was treated as in Example 1

출처 및 근거

ORD 기록
ord-627baeafa549496b8524eb7a461d6c84
출처 데이터셋
uspto-grants-1990_11
특허 번호
US04970345

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