Phenethyl bromide → Ethyl (phenethylthio)acetate

HRID 1074066

반응식

HRID 1074066 반응식
CC1C=CC(C[S:7][CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])=CC=1.Br[CH2:17][CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.CC[O-].[Na+].SCC(OCC)=O>C(O)C>[CH2:17]([S:7][CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

참가 물질

6

반응물 4

HCID 7666Phenethyl bromideHCID 12185Ethyl ThioglycolateHCID 2723922Sodium ethoxideHCID 4107274Ethyl (4-methylbenzylthio)acetate

생성물 1

HCID 304016Ethyl (phenethylthio)acetate

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The procedure is as in Example 29 for the preparation of ethyl (4-methylbenzylthio)acetate, starting with (2-bromoethyl)benzene (20 g), a 2M ethanolic solution of sodium ethylate (25 cc) and ethyl 2-mercaptoacetate (13 g) in ethanol (150 cc). Ethyl (phenethylthio)acetate (21.7 g) is thereby obtained, and is used in the crude state in the subsequent syntheses.

출처 및 근거

ORD 기록
ord-0a8a973306244cc28e3fa9cbea1165aa
출처 데이터셋
uspto-grants-1990_11
특허 번호
US04971979

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