Dimethylformamide dimethyl acetal → N-Benzyl-2-cyano-3-(dimethylamino)prop-2-enamide

반응식

[CH2:1]([NH:8][C:9](=[O:13])[CH2:10][C:11]#[N:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.CO[CH:16](OC)[N:17]([CH3:19])[CH3:18]>>[CH2:1]([NH:8][C:9](=[O:13])[C:10]([C:11]#[N:12])=[CH:16][N:17]([CH3:18])[CH3:19])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 78373Dimethylformamide dimethyl acetal

HCID 668298N-benzyl-2-cyanoacetamide

생성물 1

HCID 54269477N-Benzyl-2-cyano-3-(dimethylamino)prop-2-enamide

실험 절차

As for Example 1, N-benzyl-2-cyanoacetamide, m.p. 122°-123° C., is heated with N,N-dimethylformamide dimethylacetal to give N-benzyl-2-cyano-3-dimethylaminoacrylamide as colorless needles, m.p. 160.5°-161° C.

출처 및 근거

ORD 기록: ord-45ec4f7bfe19480b9dd640a68eedd1a9
출처 데이터셋: uspto-grants-1983_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04393217

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