Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethane → N-(2-benzylthioethyl)nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethane | HCID 6324 | — |
| 반응물 | 2-(Benzylsulfanyl)ethan-1-amine | HCID 31198 | — |
| 반응물 | Ethyl Nicotinate | HCID 69188 | — |
| 생성물 | N-(2-benzylthioethyl)nicotinamide | HCID 20495567 | — |
반응 단계
30 grams of ethyl nicotinate and 80 grams of 2-benzylthio ethylamine are heated for 12 hours at 170°-180° C. The ethane liberated during the reaction is removed by means of a Dean Stark apparatus. After cooling, the reaction mixture is dissolved in 400 cc of carbon tetrachloride; by addition of petroleum ether, the N-(2-benzylthioethyl)nicotinamide crystallizes: 47 g. By crystallization in a mixture of carbon tetrachloride and cyclohexane, there are recovered colorless crystals of the above product melting at 79° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04394520 |
| 출처 데이터셋 | uspto-grants-1983_07 |
| ORD ID | ord-ad9243e8516948e18e4b28ea6ec3827a |
| 출처 메모 | uspto-grants-1983_07 |