Phosphorus sulfide (P2S5) → HCID 20494272, 화합물
반응식
[Cl:1][C:2]1[C:3](=O)[NH:4][C:5](=[O:9])[NH:6][C:7]=1[CH3:8].P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:12]>O1CCOCC1>[Cl:1][C:2]1[C:3](=[S:12])[NH:4][C:5](=[O:9])[NH:6][C:7]=1[CH3:8]참가 물질
4
실험 절차
5-Chloro-6-methyluracil (prepared as described in Johnson, B. T. J. Amer. Chem. Soc. 65 (1943) (1220) (0.018 mol) and phosphorus pentasulphide (0.019 mol) were heated together in refluxing dioxan (200 ml) for 45 min. The hot reaction mixture was then filtered and the cold filtrate concentrated and diluted with ether. The participate collected after a few hours in the cold, was recrystallised from water; yield 75% m.p. 297°-300° C. (decomp.); (Found: C, 32.69; H, 3.96. Calc. for C5H5ClN2OS.1/2H2O: C, 32.35; H, 3.25).
후처리
- filtrationThe hot reaction mixture was then filtered
- concentrationthe cold filtrate concentrated
- additiondiluted with ether
- customThe participate collected after a few hours in the cold,
- customwas recrystallised from water
출처 및 근거
- ORD 기록
- ord-4144011a89304f38a047939c568a2deb
- 출처 데이터셋
- uspto-grants-1983_07
- 특허 번호
- US04395406
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