5-Fluorouracil → 5-Fluoro-4-thiouracil
반응식
[F:1][C:2]1[C:3](=O)[NH:4][C:5](=[O:8])[NH:6][CH:7]=1.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:11].O1CCOCC1>N1C=CC=CC=1>[F:1][C:2]1[C:3](=[S:11])[NH:4][C:5](=[O:8])[NH:6][CH:7]=1참가 물질
5
실험 절차
Prepared from 5-fluorouracil by the method of Ueda and Fox (see above) using phosphorus pentasulphide in pyridine. We find that dioxan is a better solvent in this reaction in which case the yield was 80% of a more pure product.
후처리
- customin this reaction in which case the yield was 80% of a more pure product
출처 및 근거
- ORD 기록
- ord-2a6589d625fe475292c6216055f43040
- 출처 데이터셋
- uspto-grants-1983_07
- 특허 번호
- US04395406
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