Ethanol → HCID 86754078, 화합물

HRID 1075699노트

반응식

HRID 1075699 반응식
C([NH:4][CH2:5][CH2:6][O:7][CH2:8][C:9]([O-:11])=[O:10])(=O)C.[Na+:12].[OH-].[Na+].CCO>O>[NH2:4][CH2:5][CH2:6][O:7][CH2:8][C:9]([O-:11])=[O:10].[Na+:12]

참가 물질

5

반응물 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 86754077HCID 86754077, 화합물

생성물 1

HCID 86754078HCID 86754078, 화합물

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
100 °C

실험 절차

52 g of sodium 5-acetylamino-3-oxapentanoate were dissolved in 200 ml of water. 11.4 g of NaOH were added at 20° C., and the reaction mixture was then heated at 100° C. for 8 h until precursor was no longer detectable. Then 200 ml of EtOH were added and the pH was adjusted to about 6, resulting in pure crystals of sodium 5-amino-3-oxapentanoate. The crude product resulting after removal of the solvent by distillation as a mixture with sodium acetate weighing 63.3 g (corresponding to 100% of theory) could be employed without prior precipitation for the subsequent reaction.

출처 및 근거

ORD 기록
ord-73112dd8f6c24967aaee3dc92f68f0da
출처 데이터셋
uspto-grants-1999_05
특허 번호
US05907055

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