Pyrrolidine → HCID 19428538, 화합물

반응식

Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[C:4]([NH:9][CH2:10][C:11]([CH3:14])([CH3:13])[CH3:12])[N:3]=1.[NH:15]1[CH2:19][CH2:18][CH2:17][CH2:16]1>>[Cl:8][C:6]1[CH:7]=[C:2]([N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)[N:3]=[C:4]([NH:9][CH2:10][C:11]([CH3:14])([CH3:13])[CH3:12])[N:5]=1

참가 물질

반응물 2

HCID 31268Pyrrolidine

HCID 19428516HCID 19428516, 화합물

생성물 1

HCID 19428538HCID 19428538, 화합물수율 96.7%

실험 절차

4,6-Dichloro-2-(2,2-dimethylpropylamino)pyrimidine is reacted with pyrrolidine as described in Example 7 to give the title compound in a yield of 96.7%, m.p.:147°-150° C.

출처 및 근거

ORD 기록: ord-9a2e0a0d7e874d4fae3fab626278347f
출처 데이터셋: uspto-grants-1996_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05547949

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