m-Anisoyl chloride → 3-Methoxybenzamide

HRID 1078362노트

반응식

HRID 1078362 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=1)[C:6](Cl)=[O:7].C([O-])(=O)C.[NH4+:16]>CC(C)=O.ClCCl>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=1)[C:6]([NH2:16])=[O:7]

참가 물질

5

반응물 2

HCID 74374m-Anisoyl chlorideHCID 517165Ammonium Acetate

생성물 1

HCID 984873-Methoxybenzamide수율 49.8%

시약·촉매·용매 2

HCID 180Acetone용매HCID 6344Dichloromethane용매

실험 절차

17 g of 3-methoxybenzoyl chloride were dissolved in 200 ml acetone. 15.5 g of ammonium acetate were added to the solution and the reaction mixture was stirred for several hours at room temperature. Then it was dissolved in dichloromethane. The dichloromethane phase was dried by adding sodium carbonate and concentrated. 7.5 g of 3-methoxybenzamide were obtained as a colorless solid.

후처리

  1. dry with materialThe dichloromethane phase was dried
  2. additionby adding sodium carbonate
  3. concentrationconcentrated

출처 및 근거

ORD 기록
ord-228169d585f3459db6433751facf9e90
출처 데이터셋
uspto-grants-1996_08
특허 번호
US05547967

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