4'-Hydroxyacetophenone → 2-Bromo-1-(4-hydroxyphenyl)ethanone
반응식
[CH3:1][C:2]([C:4]1[CH:5]=[CH:6][C:7]([OH:10])=[CH:8][CH:9]=1)=[O:3].[Br:11]Br>O1CCOCC1>[Br:11][CH2:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1)=[O:3]참가 물질
4
실험 절차
To a solution of 4-hydroxyacetophenone (2.5 g, 18.3 mmol) (Aldrich) in dioxane (10 mL) was added dropwise a solution of bromine (3.22 g, 20.1 mmol) in dioxane (20 mL). After stirring for 10 minutes, the mixture was concentrated in vacuo and the residue was recrystalized from methanol to provide 2-bromo-1-(4-hydroxyphenyl)ethanone (1.73 g, 44% yield).
후처리
- concentrationthe mixture was concentrated in vacuo
- customthe residue was recrystalized from methanol
출처 및 근거
- ORD 기록
- ord-1467451901b34110b095a0f9bc4d4385
- 출처 데이터셋
- uspto-grants-2006_08
- 특허 번호
- US07094896B2
반응 노트
불러오는 중…