Fluorobenzene → HCID 10824374, 화합물

HRID 1081331노트

반응식

HRID 1081331 반응식
[CH3:1][N:2]1[CH:6]=[CH:5][C:4]2[C:7]([O:9][C:10](=[O:11])[C:3]1=2)=[O:8].[F:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[Cl-].[Al+3].[Cl-].[Cl-]>>[F:12][C:13]1[CH:18]=[CH:17][C:16]([C:7]([C:4]2[CH:5]=[CH:6][N:2]([CH3:1])[C:3]=2[C:10]([OH:9])=[O:11])=[O:8])=[CH:15][CH:14]=1

참가 물질

4

반응물 3

HCID 10008FluorobenzeneHCID 6451240Aluminum(III) ChlorideHCID 450820111-Methyl-1H-furo[3,4-B]pyrrole-4,6-dione

생성물 1

HCID 10824374HCID 10824374, 화합물

실험 절차

1-Methyl-2,3-pyrroledicarboxylic anhydride and fluorobenzene were subjected to substantially the same reaction and process as in Reference Example 1 Process 1 in the presence of aluminum chloride to give 3-(4-fluorobenzoyl)-1-methyl-2-pyrrolecarboxylic acid as colorless crystals.

출처 및 근거

ORD 기록
ord-db52c647f4ed4af390356038fb483918
출처 데이터셋
uspto-grants-1996_12
특허 번호
US05585385

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