Sodium Hydroxide → HCID 178488132, 화합물

HRID 1081674노트

반응식

HRID 1081674 반응식
Cl.Cl[CH2:3][C:4]1[C:9]([CH3:10])=[C:8]([S:11][CH2:12][C:13]2[O:14][CH:15]=[CH:16][CH:17]=2)[CH:7]=[CH:6][N:5]=1.[CH3:18][O:19][C:20]1[CH:29]=[CH:28][C:23]2[NH:24][C:25]([SH:27])=[N:26][C:22]=2[CH:21]=1.[OH-].[Na+]>C(O)C>[CH3:18][O:19][C:20]1[CH:29]=[CH:28][C:23]2[NH:24][C:25]([S:27][CH2:3][C:4]3[C:9]([CH3:10])=[C:8]([S:11][CH2:12][C:13]4[O:14][CH:15]=[CH:16][CH:17]=4)[CH:7]=[CH:6][N:5]=3)=[N:26][C:22]=2[CH:21]=1

참가 물질

5

반응물 3

HCID 14798Sodium HydroxideHCID 224607712-Chloromethyl-4-(2-furylmethylthio)-3-methylpyridine hydrochlorideHCID 178488140HCID 178488140, 화합물

생성물 1

HCID 178488132HCID 178488132, 화합물수율 81%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

2-Chloromethyl-4-(2-furylmethylthio)-3-methylpyridine hydrochloride, 5-methoxy-2-mercapto-1H-benzimidazole and sodium hydroxide are reacted in ethanol at 60° C. for 4 h. This gives the title compound as a colorless solid. Yield: 81%, m.p. 106-108° C.

출처 및 근거

ORD 기록
ord-111c6a5104aa44239d80120d05ef367c
출처 데이터셋
uspto-grants-1996_12
특허 번호
US05587389

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