Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 4,8-Bis(trifluoromethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepin-11-thione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Phosphorus sulfide (P2S5) | HCID 14817 | — |
| 반응물 | 4,8-Bis(trifluoromethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepin-11-one | HCID 19969457 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 4,8-Bis(trifluoromethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepin-11-thione | HCID 23362004 | 50.8% |
반응 단계
4,8-Bis(trifluoromethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepin-11-one (0.54 g) was dissolved in pyridine (15 ml). Phosphorus pentasulphide (0.60 g) was added to the solution and the whole was stirred under reflux for 6 hours, then cooled and left overnight. Addition of water (40 ml) and cooling gave a yellow solid which was filtered off, washed with water and recrystallised from ethanol to give the product as yellow needles (0.26 g, m/s. M- =379).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05589474 |
| 출처 데이터셋 | uspto-grants-1996_12 |
| ORD ID | ord-1fe3702d00fa43e08fd4e1296acf6dd0 |
| 출처 메모 | uspto-grants-1996_12 |