Methyl cyclohexanecarboxylate → Cyclohexanecarbohydrazide

HRID 1085112

반응식

HRID 1085112 반응식
[CH:1]1([C:7]([O:9]C)=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:11][NH2:12].O>C(O)(C)C>[CH:1]1([C:7]([NH:11][NH2:12])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

4

반응물 2

HCID 20748Methyl cyclohexanecarboxylateHCID 24654Hydrazine hydrate (1:1)

생성물 1

HCID 240039Cyclohexanecarbohydrazide

시약·촉매·용매 1

HCID 3776Isopropanol용매

실험 절차

28 Grams of methyl cyclohexylcarboxylate and 15 g of 85%-NH2NH2.H2O were dissolved in 50 ml of isopropyl alcohol, and the solution was refluxed by heating for 10 hours. The reaction mixture was concentrated, and the crystals precipitated by adding water were collected by filtration, then the crystals were washed with water, then recrystallized from water to yield 20 g of cyclohexanecarbohydrazide in the form of colorless needle-like crystals.

후처리

  1. temperaturethe solution was refluxed
  2. temperatureby heating for 10 hours
  3. concentrationThe reaction mixture was concentrated
  4. customthe crystals precipitated
  5. additionby adding water
  6. filtrationwere collected by filtration
  7. washthe crystals were washed with water
  8. customrecrystallized from water

출처 및 근거

ORD 기록
ord-2cb69bdc3bbd47d58486164b0447b5d6
출처 데이터셋
uspto-grants-1991_04
특허 번호
US05008274

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