Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 1,3-Dimethyl-6-(piperazin-1-yl)pyrimidine-2,4(1H,3H)-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | N-(2-Bromoethyl)-p-nitrobenzamide | HCID 458985 | — |
| 반응물 | 1,3-Dimethyl-6-(piperazin-1-yl)pyrimidine-2,4(1H,3H)-dione | HCID 12816873 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 1,3-Dimethyl-6-(piperazin-1-yl)pyrimidine-2,4(1H,3H)-dione | HCID 12816873 | — |
| 생성물 | 1,3-dimethyl-6-[4-(4-nitrophenyl)piperazin-1-yl]-2,4(1H,3H)-pyrimidinedione | HCID 20061078 | — |
반응 단계
A mixture of 1.3 g of the compound 46 obtained in the paragraph (1), 1.8 g of 1,3-dimethyl-6-(1-piperazinyl)-2,4(1H,3H)pyrimidinedione (compound 37), 1.3 ml of triethylamine and 10 ml of isopropanol was heated under reflux for 3 hours.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05008267 |
| 출처 데이터셋 | uspto-grants-1991_04 |
| ORD ID | ord-2bd4fbbbc3894fdaabbf7c5db9213d68 |
| 출처 메모 | uspto-grants-1991_04 |