Methyl iodide → 3-(N,N,N-trimethylammonio)-1-(3,4,5-trimethoxyphenyl)propan-1-one iodide

HRID 1085627

반응식

HRID 1085627 반응식
[CH3:1][N:2]([CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[C:12]([O:14][CH3:15])[C:11]([O:16][CH3:17])=[C:10]([O:18][CH3:19])[CH:9]=1)=[O:7])[CH3:3].[CH3:20][I:21]>CCOCC>[I-:21].[CH3:1][N+:2]([CH2:4][CH2:5][C:6]([C:8]1[CH:9]=[C:10]([O:18][CH3:19])[C:11]([O:16][CH3:17])=[C:12]([O:14][CH3:15])[CH:13]=1)=[O:7])([CH3:20])[CH3:3]

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 4123063-(Dimethylamino)-1-(3,4,5-trimethoxyphenyl)propan-1-one

생성물 1

HCID 104092223-(N,N,N-trimethylammonio)-1-(3,4,5-trimethoxyphenyl)propan-1-one iodide

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

An ambient temperature solution of 3-(N,N-dimethylamino)-1-(3,4,5-trimethoxyphenyl)-propan-1-one (242.5 g, 0.91 mole) in Et2O (1.62 L) under nitrogen atmosphere was treated with methyl iodide (83 mL, 1.27 mole) and stirred for 2 hours. The resulting mixture was filtered and dried under high vacuum overnight at room temperature to provide 3-(N,N,N-trimethylammonio)-1-(3,4,5-trimethoxyphenyl)propan-1-one iodide as a white solid which was used without further purification.

후처리

  1. filtrationThe resulting mixture was filtered
  2. customdried under high vacuum overnight at room temperature

출처 및 근거

ORD 기록
ord-36f65644184048028aa490471da7b6af
출처 데이터셋
uspto-grants-1991_04
특허 번호
US05010100

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