Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methoxynaphthalen-1-ylmethylamine → 4,6-Dichloro-5-(4-methoxy-1-naphthylmethylamino)-3(2H)pyridazinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methoxynaphthalen-1-ylmethylamine | HCID 59139 | — |
| 반응물 | 3,4,5-Trichlor-6-hydroxypyridazin | HCID 11106349 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4,6-Dichloro-5-(4-methoxy-1-naphthylmethylamino)-3(2H)pyridazinone | HCID 9884758 | — |
반응 단계
A mixture comprising 800 mg of 4,5,6-trichloro-3(2H)pyridazinone, 2.68 g of 4-methoxy-1-naphthylmethylamine and 10 ml of ethanol, was refluxed under stirring for 4 hours. After cooling, precipitated crystals were collected by filtration. Then, the product was dissolved in hot ethyl acetate and treated by silica gel. The filtrate was concentrated, and precipitated crystals were collected by filtration to obtain 330 mg of the above identified compound as colorless crystals having a melting point of from 228° to 231° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05011839 |
| 출처 데이터셋 | uspto-grants-1991_04 |
| ORD ID | ord-f83b4264c56b4aef9b9b6fb6f5dcebcc |
| 출처 메모 | uspto-grants-1991_04 |