Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Fluorophenol → 4-(2-Fluoro-phenoxy)benzophenone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Fluorophenol | HCID 9707 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 2-Fluorobenzophenone | HCID 67650 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 4-(2-Fluoro-phenoxy)benzophenone | HCID 15143247 | 87% |
반응 단계
All the components (301 g of 46 percent aqueous KOH, 501 g of fluorobenzophenone, 800 mL of DMSO, and 269 g of fluorophenol), plus 5 mole percent BHT (25 g) were mixed together under a nitrogen atmosphere and distillation of water was carried out at a maximum temperature of 80° C. Reaction continued at 70° C. for a total of 12 hr. Purification by lights distillation gave an 87 percent yield of 4-(2-fluoro-phenoxy)benzophenone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05012017 |
| 출처 데이터셋 | uspto-grants-1991_04 |
| ORD ID | ord-7d6362f073dc417b932b7eb13636c568 |
| 출처 메모 | uspto-grants-1991_04 |