Ethanolamine → 2-Pentyl-2-oxazoline

HRID 1086420

반응식

HRID 1086420 반응식
[C:1](#[N:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].C(C#N)CCCCCCCCCC.[CH2:21]([CH2:23]N)[OH:22]>O.O.C([O-])(=O)C.[Zn+2].C([O-])(=O)C>[CH2:2]([C:1]1[O:22][CH2:21][CH2:23][N:7]=1)[CH2:3][CH2:4][CH2:5][CH3:6]

참가 물질

5

반응물 3

HCID 700EthanolamineHCID 12352HexanenitrileHCID 17092Dodecanenitrile

생성물 1

HCID 146517902-Pentyl-2-oxazoline수율 60%

시약·촉매·용매 1

HCID 2724192Zinc acetate (USP)촉매

실험 절차

9.72 g (100 mmoles) of hexanenitrile was substituted for undecyl cyanide in Example 1 and the reaction was repeated with 6.11 g (100 mmoles) of ethanolamine and 549 mg (2.5 mmoles) of zinc acetate dihydrate under identical conditions. At the end of the reaction the product was worked up as before and distilled at 73° C./10 mm to give 8.2 g (60%) of 2-pentyl-2-oxazoline.

후처리

  1. customAt the end of the reaction the product
  2. distillationdistilled at 73° C./10 mm

출처 및 근거

ORD 기록
ord-5dac6adbfadc472fa1136602ebb1d453
출처 데이터셋
uspto-grants-1991_07
특허 번호
US05030629

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