Epichlorohydrin → 3-(2-Benzyl-4-chlorophenoxy)-1,2-epoxypropane

HRID 1087405

반응식

HRID 1087405 반응식
[CH2:1]([C:8]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:9]=1[OH:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:17][CH:18]1[O:20][CH2:19]1.C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[CH2:1]([C:8]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:9]=1[O:15][CH2:17][CH:18]1[O:20][CH2:19]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

5

반응물 3

HCID 7835EpichlorohydrinHCID 8425ChloropheneHCID 11430Potassium Carbonate

생성물 1

HCID 143699403-(2-Benzyl-4-chlorophenoxy)-1,2-epoxypropane

시약·촉매·용매 1

HCID 6569Methyl Ethyl Ketone용매

실험 절차

A suspension containing 21.87 g of 2-benzyl-4-chlorophenol, 27.76 g of 1-chloro-2,3-epoxypropane and 27.64 g of potassium carbonate in 200 ml of butanone is refluxed for 12 hours. The inorganic salts formed are filtered off and drained. The solvent and excess 1-chloro-2,3-epoxypropane are evaporated off under vacuum and the residue is distilled at between 160° C. and 180° C. under 0.01 mm of mercury.

후처리

  1. temperatureis refluxed for 12 hours
  2. customThe inorganic salts formed
  3. filtrationare filtered off
  4. customThe solvent and excess 1-chloro-2,3-epoxypropane are evaporated off under vacuum
  5. distillationthe residue is distilled at between 160° C. and 180° C. under 0.01 mm of mercury

출처 및 근거

ORD 기록
ord-f9f619d136424341bc05c2fa1bf5aa73
출처 데이터셋
uspto-grants-1991_07
특허 번호
US05036077

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