Water → 2-(2-Iodo-5-methoxyphenyl)acetic acid
반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([OH:12])=[O:11])[CH:6]=[CH:7][CH:8]=1.[I:13]Cl.O>C(O)(=O)C.II>[I:13][C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][C:5]=1[CH2:9][C:10]([OH:12])=[O:11]참가 물질
6
실험 절차
A solution of 45 g (0.27 mole) of 3-methoxybenzeneacetic acid, 52.6 g (0.32 mole) of iodine monochloride and 1 g of iodine was allowed to stand in 500 ml of glacial acetic acid for six days at room temperature. The reaction was poured into water and the solid collected. It was recrystallized from toluene to give 51 g of crystalline 2-iodo-5-methoxybenzeneacetic acid, mp 133.5°-134.5° C. (65% yield).
후처리
- customthe solid collected
- customIt was recrystallized from toluene
출처 및 근거
- ORD 기록
- ord-cfb22fad5f8146dfa3eee01c196fc344
- 출처 데이터셋
- uspto-grants-1990_10
- 특허 번호
- US04960798
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