Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
8-(Bromomethyl)quinoline → 8-Quinolinemethanol,acetate(ester)
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 8-(Bromomethyl)quinoline | HCID 346914 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 8-Quinolinemethanol,acetate(ester) | HCID 15053140 | 85.5% |
반응 단계
8-Bromomethylquinoline (1.11 g) and sodium acetate (0.82 g) were suspended and dissolved in dimethyl formamide, and heated for 2 hours at 80° to 90° C. After completion of the reaction, dimethyl formamide was distilled off, and the residue was extracted with a mixed solvent of ethyl acetate-toluene (3:1). The solvent was distilled off to give 8-acetoxymethylquinoline (0.86 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04963566 |
| 출처 데이터셋 | uspto-grants-1990_10 |
| ORD ID | ord-d22eefa4c1ef4d9eb230b06c54d466d0 |
| 출처 메모 | uspto-grants-1990_10 |