Sodium Chloride → 2-Amino-6-methoxyphenol
반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([N+:9]([O-])=O)[C:4]=1[OH:12].S(S([O-])=O)([O-])=O.[Na+].[Na+].[Cl-].[Na+]>O.CO>[NH2:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[C:4]=1[OH:12]참가 물질
6
반응 조건
- 온도
- 60 °C
실험 절차
To a suspension of 4.72 g of 2-methoxy 6-nitrophenol in a mixture of 100 ml of water and 30 ml of methanol was added 29.3 g of sodium dithionite. The mixture was stirred at 60° C. until it became a uniform and colorless solution. To the reaction mixture was added a saturated aqueous solution of sodium chloride. The mixture was extracted with ethyl acetate and dried over anhydrous sodium sulfate. After the drying agent was filtered off, the solvent was distilled off under reduced pressure to give 3.65 g of crude 2-amino-6-methoxyphenol.
후처리
- extractionThe mixture was extracted with ethyl acetate
- dry with materialdried over anhydrous sodium sulfate
- filtrationAfter the drying agent was filtered off
- distillationthe solvent was distilled off under reduced pressure
출처 및 근거
- ORD 기록
- ord-c630a99d6e8146909aed3ba1e297fec9
- 출처 데이터셋
- uspto-grants-1990_10
- 특허 번호
- US04965261
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