Ethanol → 1-(3,5-Dichlorophenyl)-4-ethoxycarbonyl-5-pyrazolecarboxamide
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[C:1]([C:4]1[CH:5]=[N:6][N:7]([C:12]2[CH:17]=[C:16]([Cl:18])[CH:15]=[C:14]([Cl:19])[CH:13]=2)[C:8]=1[C:9]([NH2:11])=[O:10])([OH:3])=[O:2].[CH2:20](O)[CH3:21]>Cl>[Cl:19][C:14]1[CH:13]=[C:12]([N:7]2[C:8]([C:9]([NH2:11])=[O:10])=[C:4]([C:1]([O:3][CH2:20][CH3:21])=[O:2])[CH:5]=[N:6]2)[CH:17]=[C:16]([Cl:18])[CH:15]=1참가 물질
4
실험 절차
Two g of the compound of Example 2 was suspended in 80 ml of absolute ethanol and hydrogen chloride 9as was bubbled through for 5 minutes. The mixture was then heated under reflux for 2 hours and cooled, and was then filtered. The solids were collected and dried to obtain 1.25 g of the desired product, m.p. 164°-166°.
후처리
- customwas bubbled through for 5 minutes
- temperatureThe mixture was then heated
- temperatureunder reflux for 2 hours
- temperaturecooled
- filtrationwas then filtered
- customThe solids were collected
- customdried
출처 및 근거
- ORD 기록
- ord-3c7f6434411a492c880df0fabf004958
- 출처 데이터셋
- uspto-grants-1990_10
- 특허 번호
- US04966623
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