Hydrogen Bromide → HCID 14719549, 화합물

HRID 1089471노트

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HRID 1089471 반응식
C[O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]([C:13]3[CH:18]=[CH:17][C:16]([O:19]C)=[C:15]([O:21]C)[CH:14]=3)[CH2:8][NH:9][CH2:10]2)=[CH:5][CH:4]=1.[BrH:23]>>[BrH:23].[OH:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]([C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:21])[CH:14]=3)[CH2:8][NH:9][CH2:10]2)=[CH:5][CH:4]=1

참가 물질

3

반응물 2

HCID 260Hydrogen BromideHCID 147195487-Methoxy-4-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline

생성물 1

HCID 14719549HCID 14719549, 화합물

실험 절차

640 mg of 7-methoxy-4-(3,4-dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline was dissolved in 13 ml of 48% aqueous hydrogen bromide, and the mixture was heated under reflux under an argon gas stream for 3 hours. The reaction solution was cooled, and crystals which separated out were collected, affording 580 mg of 7-hydroxy-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline hydrobromide.

후처리

  1. temperaturethe mixture was heated
  2. temperatureunder reflux under an argon gas stream for 3 hours
  3. temperatureThe reaction solution was cooled
  4. customcrystals which separated out
  5. customwere collected

출처 및 근거

ORD 기록
ord-f7fdce6d47d340c5bb6da0e94e441355
출처 데이터셋
uspto-grants-1990_10
특허 번호
US04966904

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