Diethyl Ether → HCID 178461648, 화합물

HRID 1089868노트

반응식

HRID 1089868 반응식
[CH3:1][N:2]([C@@H:4]([C-:6]1[CH:10]=[CH:9][CH:8]=[CH:7]1)[CH3:5])[CH3:3].[CH-:11]1[CH:15]=[CH:14][CH:13]=[CH:12]1.[Fe+2:16].C[I:18].C(OCC)C>CC(C)=O>[I-:18].[CH3:1][N+:2]([C@@H:4]([C-:6]1[CH:10]=[CH:9][CH:8]=[CH:7]1)[CH3:5])([CH3:11])[CH3:3].[CH-:11]1[CH:15]=[CH:14][CH:13]=[CH:12]1.[Fe+2:16]

참가 물질

5

반응물 3

HCID 3283Diethyl EtherHCID 6328Methyl iodideHCID 15823231cyclopenta-1,3-diene;(1R)-1-cyclopenta-2,4-dien-1-yl-N,N-dimethylethanamine;iron(2+)

생성물 1

HCID 178461648HCID 178461648, 화합물수율 200%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

20.0g (77.8 mmol) of (R)-N,N-dimethyl-1-ferrocenyl-ethylamine was added under argon atmosphere to a glass vessel (atmospheric pressure use only) with an agitator and dissolved in acetone 37 ml. After cooling with ice water, methyl iodide 21 ml (337 mmol) was added to the vessel and reacted for 15 minutes under cooling with ice water. After reaction, ethylether 160 ml was added to the vessel and crystals were deposited. The crystals were collected by filtration to obtain (R)-N,N,N-trimethyl-1-ferrocenylethylammonium iodide 31.0 g (77.8 mmol)(yield: 100%).

후처리

  1. additionwas added to the vessel
  2. customreacted for 15 minutes
  3. additionwas added to the vessel and crystals
  4. filtrationThe crystals were collected by filtration

출처 및 근거

ORD 기록
ord-c1055095b1ca4e69b8909039a5b3a9bd
출처 데이터셋
uspto-grants-1992_01
특허 번호
US05079359

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