Hydrochloric Acid → HCID 178486502, 화합물

HRID 1091517

반응식

HRID 1091517 반응식
[CH3:1][O:2][C:3]1[C:4]([O:25][CH3:26])=[CH:5][C:6]2[C:7]3[N:8]([CH2:22][CH2:23][N:24]=3)[C:9](/[CH:13]=[C:14](/[C:16]3[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=3)\[OH:15])=[N:10][C:11]=2[CH:12]=1.[ClH:27]>O1CCOCC1>[ClH:27].[CH3:1][O:2][C:3]1[C:4]([O:25][CH3:26])=[CH:5][C:6]2[C:7]3[N:8]([CH2:22][CH2:23][N:24]=3)[C:9](/[CH:13]=[C:14](/[C:16]3[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=3)\[OH:15])=[N:10][C:11]=2[CH:12]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 178486501HCID 178486501, 화합물

생성물 1

HCID 178486502HCID 178486502, 화합물

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

To a solution of (Z)-2-(8,9-dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)-1-(3-pyridinyl)ethenol (16.8 mg, 0.05 mmol)) in dioxane (15 ml) at room temperature was added aqueous 6N HCl solution (0.05 ml). After being stirred for 30 minutes, the mixture was dried under reduced pressure to give (Z)-2-(8,9-dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)-1-(3-pyridinyl)ethenol hydrochloride (18.5 mg, quantitative) as a yellow solid.

후처리

  1. customthe mixture was dried under reduced pressure

출처 및 근거

ORD 기록
ord-4c26e1bad9fc42829ff83b4561a516e3
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08129386B2

연결된 노트

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