Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → Dimethyl pyridine-3,5-dicarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 3,5-Pyridinedicarboxylic acid | HCID 10366 | — |
| 반응물 | Ethyl acetate hexane | HCID 21226206 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Dimethyl pyridine-3,5-dicarboxylate | HCID 78339 | — |
반응 단계
3,5-Pyridinedicarboxylic acid (1.5 g, 63 mmol) and conc. H2SO4 (0.9 mL) in MeOH (15 mL) are heated in a microwave oven at 120° C. for 2 h. The solvent is evaporated to give a residue with is partitioned between ethyl acetate and sat. aq. NaHCO3. The organic phase is washed with brine, dried over Na2SO4, filtered and evaporated to give a light yellow solid. MS (LC-MS): 196 [M+H]+ TLC, Rf (ethyl acetate/hexane 1:1)=0.56.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08129411B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-e396cb8fdfe14eef972433d8f391636a |
| 출처 메모 | uspto-grants-2012_03 |