Paclitaxel → Taxane

HRID 1093935

반응식

HRID 1093935 반응식
[CH3:1][C:2]1[C@@H:19](OC([C@H](O)[C@@H](NC(C2C=CC=CC=2)=O)C2C=CC=CC=2)=O)[CH2:18][C@:14]2(O)[C:15]([CH3:17])([CH3:16])[C:3]=1[C@@H:4](OC(C)=O)[C:5]([C@@:7]1([CH3:58])[C@H:12]([C@@H:13]2OC(C2C=CC=CC=2)=O)[C@:11]2(OC(C)=O)[CH2:51]O[C@@H:10]2[CH2:9][C@@H:8]1O)=O.CC1[C@@H](OC([C@H](O)[C@@H](NC(OC(C)(C)C)=O)C2C=CC=CC=2)=O)C[C@]2(O)C(C)(C)C=1[C@@H](O)C([C@@]1(C)[C@H]([C@@H]2OC(C2C=CC=CC=2)=O)[C@]2(OC(C)=O)CO[C@@H]2C[C@@H]1O)=O>>[CH3:51][C@H:11]1[C@H:12]2[CH2:13][C@H:14]3[C:15]([CH3:16])([CH3:17])[C@@H:3]([CH2:4][CH2:5][C@:7]2([CH3:58])[CH2:8][CH2:9][CH2:10]1)[C@H:2]([CH3:1])[CH2:19][CH2:18]3

참가 물질

3

반응물 2

HCID 36314PaclitaxelHCID 148124Docetaxel

생성물 1

HCID 9548828Taxane

실험 절차

Under the above test conditions, both paclitaxel and docetaxel were completely insoluble.

출처 및 근거

ORD 기록
ord-deb8f63a36ce4dc9b34a0d713994aae1
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08133888B2

연결된 노트

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