4-Nitroisophthalic acid → 4-Aminobenzene-1,3-dioic acid

HRID 1094730

반응식

HRID 1094730 반응식
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:10])=[O:9])=[CH:6][C:5]=1[C:13]([OH:15])=[O:14])([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:10])=[O:9])=[CH:6][C:5]=1[C:13]([OH:15])=[O:14]

참가 물질

4

반응물 1

HCID 30624384-Nitroisophthalic acid

생성물 1

HCID 113558524-Aminobenzene-1,3-dioic acid

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

To a solution of 4-nitro isophthalic acid (4 g, 18.95 mmol) in MeOH (200 mL) was added Pd/C (20%) and the mixture was hydrogenated at RT over night. The reaction mixture was filtered through Celite and filtrate concentrated under vacuum to give 4-amino isophthalic acid in 60% as a solid.

후처리

  1. waitthe mixture was hydrogenated at RT over night
  2. filtrationThe reaction mixture was filtered through Celite and filtrate
  3. concentrationconcentrated under vacuum

출처 및 근거

ORD 기록
ord-a70aad4b64f84b4ba0494f54b48628cb
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08133998B2

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