Acetic Anhydride → Ethyl (acetyloxy)(4-chloro-3-nitrophenyl)acetate

HRID 1096473노트

반응식

HRID 1096473 반응식
[CH2:1]([O:3][C:4](=[O:17])[CH:5]([C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[C:9]([N+:14]([O-:16])=[O:15])[CH:8]=1)[OH:6])[CH3:2].[C:18](OC(=O)C)(=[O:20])[CH3:19]>N1C=CC=CC=1>[CH2:1]([O:3][C:4](=[O:17])[CH:5]([O:6][C:18](=[O:20])[CH3:19])[C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[C:9]([N+:14]([O-:16])=[O:15])[CH:8]=1)[CH3:2]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 86609828Ethyl (4-chloro-3-nitrophenyl)(hydroxy)acetate

생성물 1

HCID 86609827Ethyl (acetyloxy)(4-chloro-3-nitrophenyl)acetate

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

To a solution (6 mL) of the compound (1.46 g) prepared in Example 22 in pyridine, acetic anhydride (2 mL) was added, and the mixture was stirred for 1 hour at room temperature. The title compound (135 mg) having the following physical data was obtained by concentrating the reaction mixture and azeotroping in toluene.

출처 및 근거

ORD 기록
ord-555d4c3cd5e8463eb2a81316404c49a5
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08138335B2

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