Hydrochloric Acid → HCID 66811347, 화합물

HRID 1098709

반응식

HRID 1098709 반응식
C[O:2][C:3](=[O:20])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([NH:16]C(=O)C)=[CH:12][CH:11]=1.[ClH:21]>>[ClH:21].[NH2:16][C:13]1[CH:12]=[CH:11][C:10]([O:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:20])=[O:2])=[CH:15][CH:14]=1

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 497644916-(4-Acetylaminophenoxy)-hexanoic acid methyl ester

생성물 1

HCID 66811347HCID 66811347, 화합물수율 55.6%

반응 조건

온도
10 °C

실험 절차

6-(4-acetylaminophenoxy)-hexanoic acid methyl ester 15 (290 g, 1.04 mol), in conc. HCl (7.12 L) was refluxed for 48 hours. Excess conc. HCl was distilled off in vacuum and filtered hot. The mixture was cooled to 10° C., filtered and dried to give pure 16 (150 g, 55.6%) as a brown powder with an m.p between 155-160° C.

후처리

  1. distillationExcess conc. HCl was distilled off in vacuum
  2. filtrationfiltered hot
  3. filtrationfiltered
  4. customdried

출처 및 근거

ORD 기록
ord-5a3028a75bf84e8aae1c0b01a669a30b
출처 데이터셋
uspto-grants-2012_03
특허 번호
US08143325B2

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