Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 5-iodo-6-methyl-1H-indazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 1-Acetyl-5-iodo-6-methylindazole | HCID 59339735 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 5-iodo-6-methyl-1H-indazole | HCID 59339696 | 100.8% |
반응 단계
1-Acetyl-5-iodo-6-methylindazole (1.5 g, 5.0 mmol) was stirred with ammonia (7 M in methanol, 4 mL) in methano/THF (2/1, 15 mL) for 1 h. The solution was evaporated to give the subtitle compound (1.3 g, 100%) as an off-white powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08143290B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-e5f1e91d0e524ac58251a831aedaba9c |
| 출처 메모 | uspto-grants-2012_03 |