4-Oxo-1-phenylcyclohexanenitrile → 4-Hydroxy-1-phenylcyclohexane-1-carbonitrile

HRID 1107441노트

반응식

HRID 1107441 반응식
[C:1]([C:3]1([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:8][CH2:7][C:6](=[O:9])[CH2:5][CH2:4]1)#[N:2].[BH4-].[Na+]>CO>[C:1]([C:3]1([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:8][CH2:7][CH:6]([OH:9])[CH2:5][CH2:4]1)#[N:2]

참가 물질

4

반응물 2

HCID 912824-Oxo-1-phenylcyclohexanenitrileHCID 4311764Sodium borohydride

생성물 1

HCID 124536734-Hydroxy-1-phenylcyclohexane-1-carbonitrile

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A cold (0° C.) solution of 4-cyano-4-phenylcyclohexanone (5.0 g, 25.1 mmol) in 30 ml of MeOH was treated with sodium borohydride (1.14 g, 30.1 mmol). The reaction mixture was stirred for 2 hours at room temperature and then concentrated in vacuo.

후처리

  1. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-cc8638597dbb48998b118474e48653ff
출처 데이터셋
uspto-grants-2000_05
특허 번호
US06060484

반응 노트

불러오는 중…