Hydroxyamine hydrochloride → HCID 73192201, 화합물
반응식
C([O-])(=O)C.[Na+].[CH3:6][C:7]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]2[C:8]=1[C:9](=O)[CH2:10][CH2:11][S:12]2.Cl.[NH2:20][OH:21]>O.C(O)C>[CH3:6][C:7]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]2[C:8]=1[C:9](=[N:20][OH:21])[CH2:10][CH2:11][S:12]2참가 물질
6
실험 절차
A suspension of 37.8 g of sodium acetate in water is added, at 50-60° C., to a suspension of 31.1 g (0.154 mol) of 5,7-dimethylthio-chroman-4-one and 18.5 g (0.261 mol) of hydroxylamine hydrochloride in 200 ml of ethanol. This mixture is subsequently refluxed for 30 minutes. After cooling, filtration with suction of the solid which has precipitated gives 22.2 g of 5,7-dimethylthiochroman-4-one oxime (66% of theory, purity approx. 95%) of melting point 170-174° C.
후처리
- temperatureThis mixture is subsequently refluxed for 30 minutes
- temperatureAfter cooling
- filtrationfiltration with suction of the solid which
- customhas precipitated
출처 및 근거
- ORD 기록
- ord-5c5e5b9bad72448cbe0d28df827e6962
- 출처 데이터셋
- uspto-grants-2000_05
- 특허 번호
- US06069114
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