Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → N-Octadecyl-2-(4-amino-3-tert-butyl-5-methylphenylthio)succinimide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 1-octadecyl-1H-pyrrole-2,5-dione | HCID 87118 | — |
| 반응물 | 2-Tert-butyl-4-mercapto-6-methylaniline | HCID 15324501 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-Octadecyl-2-(4-amino-3-tert-butyl-5-methylphenylthio)succinimide | HCID 15324511 | 56.4% |
반응 단계
A stirred solution of 2.8 g (14 mmol) of 2-tert-butyl-4-mercapto-6-methylaniline, 5.0 g (14 mmol) of N-octadecylmaleimide and 0.1 g (1 mmol) of triethylamine in 50 mL of toluene is heated at 50° C. for 18 hours. The solvent is removed in vacuo and the residue is purified by preparative HPLC (silica gel, 4:1, heptane:ethyl acetate eluent) to give 4.3 g (55%) of the title compound as a caramel-colored liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05321067 |
| 출처 데이터셋 | uspto-grants-1994_06 |
| ORD ID | ord-d1dbe2ed3c4b43b4a331570ee8c496ba |
| 출처 메모 | uspto-grants-1994_06 |