Water → HCID 178441902, 화합물

HRID 1110119노트

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HRID 1110119 반응식
[N+:1]([O-])([O-])=O.[Na+].[C:6]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[NH2:18])#[C:7][CH2:8][CH2:9][CH2:10][CH3:11].[OH2:19]>Cl>[CH2:8]([C:7]1[N:1]=[N:18][C:13]2[C:12]([C:6]=1[OH:19])=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:9][CH2:10][CH3:11]

참가 물질

5

반응물 3

HCID 962Water2회HCID 24268Sodium NitrateHCID 107973102-(Hex-1-yn-1-yl)aniline

생성물 1

HCID 178441902HCID 178441902, 화합물

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

반응 조건

온도
0 °C

실험 절차

A solution of 2 g of sodium nitrate in 60 ml of water was added at 0° C. to a suspension at 0° C. of 3.2 g of the product of Step A in 100 ml of concentrated hydrochloric acid. The mixture was stirred for 90 minutes at 0° C., then for one hour at 100° C. The reaction medium was poured into 100 ml of ice-cooled water, followed by separating and washing with ice-cooled water. The moist product was taken up in 100 ml of water and alkalized with concentrated ammonium hydroxide. After separating, the residue was washed with water and dried at 70° C. under reduced pressure to obtain 1.47 g of the expected product melting at 180° C.

후처리

  1. waitfor one hour at 100° C
  2. customby separating
  3. washwashing with ice-
  4. temperaturecooled water
  5. customAfter separating
  6. washthe residue was washed with water
  7. customdried at 70° C. under reduced pressure

출처 및 근거

ORD 기록
ord-b8d2622fb0d54a8889ab4f0e945e37b0
출처 데이터셋
uspto-grants-1994_06
특허 번호
US05324839

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