HCID 13785667, 화합물 → 5-Amino-4-chloro-o-cresol hydrochloride

HRID 1110646노트

반응식

HRID 1110646 반응식
[Cl:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][C:5]([OH:11])=[C:4]([CH3:12])[CH:3]=1.[H][H]>C(O)C.[Ni]>[ClH:1].[CH3:12][C:4]1[CH:3]=[C:2]([Cl:1])[C:7]([NH2:8])=[CH:6][C:5]=1[OH:11]

참가 물질

5

반응물 2

HCID 13785667HCID 13785667, 화합물HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 221538465-Amino-4-chloro-o-cresol hydrochloride

시약·촉매·용매 2

HCID 935Nickel촉매HCID 702Ethanol용매

실험 절차

5 g of 4-chloro-2-methyl-5-nitrophenol were dissolved in 200 ml of ethanol and, after addition of 0.5 g of Raney nickel, the resulting solution was catalytically hydrogenated. When the uptake of hydrogen stopped, the catalyst was separated off by filtration and the filtrate acidified with dilute hydrochloric acid. Concentration to dryness produced light beige crystals melting at 198° C. (with decomposition).

후처리

  1. customthe catalyst was separated off by filtration
  2. concentrationConcentration to dryness

출처 및 근거

ORD 기록
ord-aa05f674da744910ab5daf8dcd0502e0
출처 데이터셋
uspto-grants-1990_12
특허 번호
US04976742

반응 노트

불러오는 중…