Methyl iodide → HCID 138962835, 화합물

HRID 1111055노트

반응식

HRID 1111055 반응식
[NH2:1][C:2](=[S:12])[NH:3][C:4](=[O:11])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[CH3:13]I>CC(C)=O>[C:4]([NH:3][C:2]([S:12][CH3:13])=[NH:1])(=[O:11])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 2735473Benzoylthiourea

생성물 1

HCID 138962835HCID 138962835, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

To an 18.0 g (0.1 mole) amount of N-(aminothioxomethyl)benzamide in 300 ml of acetone was added 15.0 ml of methyl iodide (34.2 g, 0.24 mole). The mixture was heated as reflux and after about 5 minutes a solid precipitate formed. Refluxing was continued for 2 hours, then the hot reaction mixture was filtered to collect the precipitate. The precipitate was washed with two 50 ml portions of acetone, then air dried to give 28.9 g of the product as a white solid, mp 189°-190° C. (dec.).

후처리

  1. temperatureThe mixture was heated
  2. temperatureas reflux and after about 5 minutes a solid precipitate
  3. customformed
  4. temperatureRefluxing
  5. filtrationthe hot reaction mixture was filtered
  6. customto collect the precipitate
  7. washThe precipitate was washed with two 50 ml portions of acetone
  8. customair dried

출처 및 근거

ORD 기록
ord-0613752098c74cfdbdb44bbf872a653c
출처 데이터셋
uspto-grants-1990_12
특허 번호
US04977189

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