Hydrochloric Acid → Phenol, 4-(heptafluoropropyl)-

HRID 1112089노트

반응식

HRID 1112089 반응식
[C:1]([C:11]1[CH:16]=[CH:15][C:14]([O:17]C(C)=O)=[CH:13][CH:12]=1)([C:4]([C:7]([F:10])([F:9])[F:8])([F:6])[F:5])([F:3])[F:2].Cl>CO>[C:1]([C:11]1[CH:12]=[CH:13][C:14]([OH:17])=[CH:15][CH:16]=1)([C:4]([C:7]([F:8])([F:9])[F:10])([F:6])[F:5])([F:3])[F:2]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 12294033HCID 12294033, 화합물

생성물 1

HCID 12294034Phenol, 4-(heptafluoropropyl)-수율 92%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A solution of p-C3F7C6H4OC(O)CH3 (33.2 g; 0.14 mole) in CH3OH (200 ml) containing concentrated HCl (20 ml) was heated to reflux for 24 hours. After cooling and aspiration of the solvent, a brown liquid resulted (28.4 g; 99% crude yield). A gas chromatographic analysis indicated primarily one major component. Distillation provided the product p-C3F7C6H4OH (26.2 g; 92% yield).

후처리

  1. temperaturewas heated
  2. temperatureto reflux for 24 hours
  3. temperatureAfter cooling
  4. customaspiration of the solvent, a brown liquid resulted (28.4 g; 99% crude yield)
  5. distillationDistillation

출처 및 근거

ORD 기록
ord-3e1fbe057ed1442181fac9be62c5b130
출처 데이터셋
uspto-grants-1978_10
특허 번호
US04120863

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